Police say a commercial vehicle crashed into a passenger vehicle near the corner of Dugald Road and Bournais Drive around 9:30 a.m.
The 47-year-old man driving the passenger vehicle had to be extracted from car, police say.
They say the man was rushed to hospital in critical condition where he later died.
In a tweet Friday afternoon police said Dugald Road is closed to traffic between northbound Bournais Drive and southbound Beghin Avenue.
Drivers are being asked to avoid the area.
There was no word from police about how long they expect the roadway to remain closed.
Police are asking anyone with information to call investigators with the traffic division at 204-986-7085.
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